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Patent Pending PROBLEM TO BE SOLVED: To provide a method and a device for simulating in-pile environment which can achieve the simulation of the water environment in a reactor before and after the generation of hydrogen peroxide and can attain the highly accurate evaluation of structural materials for the reactor. ; SOLUTION: A high-temperature and high-pressure container 11 contains a liquid to keep it at high temperature and high pressure. A radical generation means 12 includes an ultrasonic generator placed so as to apply ultrasonic waves into the liquid or injection equipment 51 placed so as to direct a jet of high-pressure water into the liquid.