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Patent Pending PROBLEM TO BE SOLVED: To provide a means for screening the anorexigenic effect of a test material. ; SOLUTION: The method for screening the anorexigenic effect of the test material includes a step for bringing the test material into contact with a hypothalamic cell, and a step for measuring the expression level of serum/glucocorticoid-inducing kinase 1 (SGK-1) gene in the hypothalamic cell.