Serum response factor

Patent Pending Serum response factor (c-fos serum response element-binding transcription factor), also known as SRF, is a transcription factor.[1] It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors.[2] This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation.