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Patent Pending In cell biology, a vesicle is a small organelle within a cell, consisting of fluid enclosed by a lipid bilayer membrane. Vesicles can form naturally, for example, during the processes of secretion (exocytosis), uptake (phagocytosis and endocytosis) and transport of materials within the cytoplasm. Alternatively, they may be prepared artificially, in which case they are called liposomes. If there is only one phospholipid bilayer, they are called unilamellar liposome vesicles; otherwise they are called multilamellar. The membrane enclosing the vesicle is also a lamellar phase, similar to that of the plasma membrane, and vesicles can fuse with the plasma membrane to release their contents outside of the cell. Vesicles can also fuse with other organelles within the cell.