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Patent Granted An antigen is any substance that may be specifically bound by components of the immune system (antibody, lymphocytes). The term antigen arises from its ability to induce generation of antibodies (antigen = antibody generation). Despite the fact that all antigens are recognized by specific lymphocytes or by antibodies, not every antigen can evoke an immune response. Those antigens that are capable of inducing an immune response are said to be immunogenic and are called immunogens.