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Patent Granted Arrestins are a small family of proteins important for regulating signal transduction. Arrestins were first discovered as a part of a conserved two-step mechanism for regulating the activity of G protein-coupled receptors (GPCRs) in the visual rhodopsin system by Hermann Kühn and co-workers[4] and in the β-adrenergic system by Martin J. Lohse and co-workers
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