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Patent Granted Nucleobases are nitrogen-containing biological compounds (nitrogenous bases) found within nucleotides—the basic building blocks of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). Nucleobases are also found in nucleosides (a nucleobase linked to a sugar). Often simply called bases in genetics, their ability to form base-pairs and to stack upon one another lead directly to the helical structure of DNA and RNA.