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Patent Pending In enzymology, a protein geranylgeranyltransferase type I (EC 2.5.1.59) is an enzyme that catalyzes the chemical reaction geranylgeranyl diphosphate + protein-cysteine \rightleftharpoons S-geranylgeranyl-protein + diphosphate Thus, the two substrates of this enzyme are geranylgeranyl diphosphate and protein-cysteine, whereas its two products are S-geranylgeranyl-protein and diphosphate.