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Patent Granted In 2006, scientists demonstrated the successful use of telomere truncation in maize plants to produce minichromosomes that could be utilized as a platform for inserting genes into the plant genome[13] In plants, the telomere sequence is conserved which implies this strategy can be utilized to successfully construction additional minichromosomes in other plant species [14] In 2007, scientists reported success in assembling minichromosomes in vitro using the de novo method