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Patent Granted In enzymology, a dihydropyrimidinase (EC 3.5.2.2) is an enzyme that catalyzes the chemical reaction 5,6-dihydrouracil + H2O \rightleftharpoons 3-ureidopropanoate Thus, the two substrates of this enzyme are 5,6-dihydrouracil and H2O, whereas its product is 3-ureidopropanoate.