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Patent Granted Myeloperoxidase (MPO) is a peroxidase enzyme that in humans is encoded by the MPO gene.[2] Myeloperoxidase is most abundantly expressed in neutrophil granulocytes (a subtype of white blood cells).[3] It is a lysosomal protein stored in azurophilic granules of the neutrophil. MPO has a heme pigment, which causes its green color in secretions rich in neutrophils, such as pus and some forms of mucus.