Acyl-CoA synthetases

Patent Pending In enzymology, an acyl-CoA hydrolase (EC 3.1.2.20) is an enzyme that catalyzes the chemical reaction acyl-CoA + H2O \rightleftharpoons CoA + a carboxylate Thus, the two substrates of this enzyme are acyl-CoA and H2O, whereas its two products are CoA and carboxylate. This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds.