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Patent Pending Electrophoresis is the motion of dispersed particles relative to a fluid under the influence of a spatially uniform electric field.[1][2][3][4][5][6] This electrokinetic phenomenon was observed for the first time in 1807 by Ferdinand Frederic Reuss (Moscow State University),[7] who noticed that the application of a constant electric field caused clay particles dispersed in water to migrate. It is ultimately caused by the presence of a charged interface between the particle surface and the surrounding fluid. It is the basis for a number of analytical techniques used in biochemistry for separating molecules by size, charge, or binding affinity.
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