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Patent Pending Though it is known that polyamines are synthesized in cells via highly regulated pathways, their actual function is not entirely clear. As cations, they bind to DNA, and, in structure, they represent compounds with cations that are found at regularly spaced intervals (unlike, say, Mg2+ or Ca2+ , which are point charges). They have also been found to act as promoters of programmed ribosomal frameshifting during translation.