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Patent Granted Deleted in bladder cancer protein 1 is a protein that in humans is encoded by the DBC1 gene.[1][2][3][4][5] This gene is located within chromosome 9 (9q32-33), a chromosomal region that frequently shows loss of heterozygosity in transitional cell carcinoma of the bladder. It contains a 5' CpG island that may be a frequent target of hypermethylation, and it may undergo hypermethylation-based silencing in some bladder cancers.
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