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Patent Pending Myeloblastin (EC 3.4.21.76, leukocyte proteinase 3, leukocyte proteinase 4, Wegener's granulomatosis autoantigen, proteinase PR-3, proteinase-3, PMNL proteinase) is an enzyme.[1][2][3][4] This enzyme catalyses the following chemical reaction Hydrolysis of proteins, including elastin, by preferential cleavage: -Ala- > -Val- This enzyme is present in polymorphonuclear leukocyte granules.