2,5-diketo-D-gluconic acid reductase A

Patent Granted In enzymology, a 2,5-didehydrogluconate reductase (EC 1.1.1.274) is an enzyme that catalyzes the chemical reaction 2-dehydro-D-gluconate + NADP+ \rightleftharpoons 2,5-didehydro-D-gluconate + NADPH + H+ Thus, the two substrates of this enzyme are 2-dehydro-D-gluconate and NADP+, whereas its 3 products are 2,5-didehydro-D-gluconate, NADPH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor.