Respiratory syncytial virus vaccine

Patent Granted As the virus is ubiquitous in all parts of the world, avoidance of infection is not possible. A vaccine trial in 1960s using a formalin-inactivated vaccine (FI-RSV), increased disease severity in children who had been vaccinated.[17] There is much active investigation into the development of a new vaccine, but at present no vaccine exists. Some of the most promising candidates are based on temperature sensitive mutants which have targeted genetic mutations to reduce virulence.