Beta-turn mimetics

Patent Granted Beta turns (β turns, β-turns, β-bends, tight turns, reverse turns) are very common motifs in proteins and polypeptides.[1][2][3][4][5][6][7][8][9] Each consists of four amino acid residues (labelled i, i+1, i+2 and i+3). They can be defined in two ways: 1. By the possession of an inter-main-chain hydrogen bond between the CO of residue i and the NH of residue i+3.