Reversed-phase chromatography

Patent Granted Reversed-phase chromatography (also called RPC, reverse-phase chromatography, or hydrophobic chromatography) includes any chromatographic method that uses a hydrophobic stationary phase.[1] RPC refers to liquid (rather than gas) chromatography. The term "reversed-phase" has a historical background. In the 1970s, most liquid chromatography was performed using a solid support stationary phase (also called a "column") containing unmodified silica or alumina resins.