Some strategies of gene therapy require the insertion of therapeutic genes at pre-selected chromosomal target sites within the human genome. Plasmid vectors are one of many approaches that could be...
T cells or T lymphocytes are a type of lymphocyte (in turn, a type of white blood cell) that plays a central role in cell-mediated immunity. They can be distinguished from other lymphocytes, such a...
As opposed to lentiviruses, adenoviral DNA does not integrate into the genome and is not replicated during cell division. This limits their use in basic research, although adenoviral vectors are oc...
Lysosome-associated membrane glycoproteins (lamp)[1] are integral membrane proteins, specific to lysosomes, and whose exact biological function is not yet clear. Structurally, the lamp proteins con...
Immunotherapy is the "treatment of disease by inducing, enhancing, or suppressing an immune response".[1] Immunotherapies designed to elicit or amplify an immune response are classified as activati...
Apoptosis (/ˌæpəˈtoʊsɪs/;[2][3] from Ancient Greek ἀπό apo, "away from" and πτῶσις ptōsis, "falling") is the process of programmed cell death (PCD) that may occur in multicellular organisms.[4] Bio...
Chromosome 16 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 16 spans about 90 million base pairs (the building material of DNA) and...
p53 has many mechanisms of anticancer function, and plays a role in apoptosis, genomic stability, and inhibition of angiogenesis. In its anti-cancer role, p53 works through several mechanisms: I...
Calcification-resistant biomaterial
Bone cells, which are found within the bone tissue, are responsible for the make-up of the skeleton of vertebrates. There are that are made up of different bone cells: there is the compact tissue w...
Restenosis literally means the recurrence of stenosis, a narrowing of a blood vessel, leading to restricted blood flow. Restenosis usually pertains to an artery or other large blood vessel that has...
Laser induced breakdown
Muntjac cell lines
Enzyme sandwich immunoassay
An expression vector, otherwise known as an expression construct, is usually a plasmid or virus designed for protein expression in cells. The vector is used to introduce a specific gene into a targ...
Two liquids can form different types of emulsions. As an example, oil and water can form, first, an oil-in-water emulsion, wherein the oil is the dispersed phase, and water is the dispersion medium...
CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induc...
Bone precursor cells
Nucleoside analogues are molecules that act like nucleosides in DNA or RNA replication. They include a range of antiviral products used to prevent viral replication in infected cells. The most comm...