Glycogen storage disease type II (also called Pompe disease /ˈpɒmpə/ or acid maltase deficiency) is an autosomal recessive metabolic disorder[1] which damages muscle and nerve cells throughout the ...
In biochemistry and pharmacology, a ligand (from the Latin ligandum, binding) is a substance (usually a small molecule) that forms a complex with a biomolecule to serve a biological purpose. In pro...
Nitroglycerin therapy
Protein stability screening
Immunogen neutralizing HIV primary isolates
Cystic fibrosis (CF), also known as mucoviscidosis, is an autosomal recessive genetic disorder that affects mostly the lungs, and also the pancreas, liver, and intestine. Difficulty breathing is th...
Camptothecin (CPT) is a cytotoxic quinoline alkaloid which inhibits the DNA enzyme topoisomerase I (topo I). It was discovered in 1966 by M. E. Wall and M. C. Wani in systematic screening of natura...
G protein-coupled receptors (GPCRs), also known as seven-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein-linked receptors (GPLR), constitut...
Nitric oxide donors
Dicatonic molecules
The enzyme urate oxidase (UO), or uricase or factor-independent urate hydroxylase, absent in humans, catalyzes the oxidation of uric acid to 5-hydroxyisourate:[1] Uric acid + O2 + H2O → 5-hydrox...
Flap necrosis
Aptamers (from the Latin aptus - fit, and Greek meros - part) are oligonucleic acid or peptide molecules that bind to a specific target molecule. Aptamers are usually created by selecting them from...
Conducting reactions at multiple temperatures
Angio-immunotherapy
Adenoviral vectors in tumor therapy
Weight gain is an increase in body weight. This can be either an increase in muscle mass, fat deposits, or excess fluids such as water.
Anti-CD19 antibodies
Porphyrin-accumulating type herbicides
