Aptamers (from the Latin aptus - fit, and Greek meros - part) are oligonucleic acid or peptide molecules that bind to a specific target molecule. Aptamers are usually created by selecting them from...
Iron nitrosyls in blood
Hematopoietic cell malignancy
A Disintegrin and metalloproteinase domain-containing protein 10, also known as ADAM10 or CDw156 or CD156c is a protein that in humans is encoded by the ADAM10 gene. Members of the ADAM family are...
Hematopoietic stem cells (HSCs) are the blood cells that give rise to all the other blood cells and are derived from mesoderm. They are located in the red bone marrow, which is contained in the cor...
Flap necrosis
Cystic fibrosis (CF), also known as mucoviscidosis, is an autosomal recessive genetic disorder that affects mostly the lungs but also the pancreas, liver, and intestine. Difficulty breathing is the...
Nitroso refers to a functional group in organic chemistry which has the NO group attached to an organic moiety. As such, various nitroso groups can be categorized as C-nitroso compounds (e.g., nitr...
Diffuse reflectance spectroscopy
The first single-domain antibodies were engineered from heavy-chain antibodies found in camelids; these are called VHH fragments. Cartilaginous fishes also have heavy-chain antibodies (IgNAR, 'immu...
Nonfouling surface biosensor
Inducing an immune response to HIV
Neuroblastoma (NB) is the most common extracranial solid cancer in childhood and the most common cancer in infancy, with an incidence of about six hundred and fifty cases per year in the U.S.,[1] a...
Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have a negative effect on health, leading to reduced life expectancy and/or increased health proble...
Inducing neutralizing antibodies against HIV
Manipulation of droplets on a two-dimensional path was demonstrated later.[10][11] If the liquid is discretized and programmably manipulated, the approach is called "Digital Microfluidic Circuits"...
Molecules competing with ligand for binding protein
Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are the same because they are made by identical immune cells that are all clones of a unique parent cell, in contrast to polyclo...
Low-coherence interferometry
Histone deacetylase 10 is an enzyme that in humans is encoded by the HDAC10 gene.[1][2][3] Acetylation of histone core particles modulates chromatin structure and gene expression. The opposing e...
