Allergic disease

特許 係属中 PROBLEM TO BE SOLVED: To provide a degranulation inhibitory composition free from anxiety of adverse reaction, effective and safety, and to provide a composition for prevention and/or treatment of allergic disease. ; SOLUTION: The invention relates to the degranulation inhibitory composition comprising tocotrienol or its ester as an active ingredient, and to the composition for prevention and/or treatment of allergic disease.