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特許 権利維持 PROBLEM TO BE SOLVED: To provide a hollow structure containing a protein and a cell immobilized locally on the surface of the inner wall of a ready-made hollow structure. SOLUTION: The hollow structure is produced, by laminating a protein-non-adsorptive substance having negative charge to a positively charged inner wall surface of a hollow structure, to form a hollow structure having a protein-non-adsorptive inner wall surface.