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特許 権利維持 Collagen /ˈkɒlədʒɨn/ is the main structural protein of the various connective tissues in animals. (The name collagen comes from the Greek kolla meaning glue and suffix -gen denoting producing.[1][2]) As the main component of connective tissue, it is the most abundant protein in mammals,[3] making up from 25% to 35% of the whole-body protein content. Collagen, in the form of elongated fibrils, is mostly found in fibrous tissues such as tendons, ligaments and skin, and is also abundant in corneas, cartilage, bones, blood vessels, the gut, and intervertebral discs. The fibroblast is the most common cell that creates collagen. A cross-link is a bond that links one polymer chain to another. They can be covalent bonds or ionic bonds. "Polymer chains" can refer to synthetic polymers or natural polymers (such as proteins).