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特許 権利維持 About 25 mmol of calcium enters the body in a normal diet. Of this, about 40% (10 mmol) is absorbed in small intestine, and 5 mmol leaves the body in feces, netting 5 mmol of calcium a day.[2] Calcium is absorbed across the intestinal brush border membrane, passing through ion channels such as TRPV6. Calbindin is a vitamin D-dependent calcium-binding protein inside intestinal epithelial cells which functions together with TRPV6 and calcium pumps (PMCA1) in the basal membrane to actively transport calcium into the body.