Alpha 1-antichymotrypsin

特許 係属中 Alpha 1-antichymotrypsin (α1AC)[1] is an alpha globulin glycoprotein that is a member of the serpin superfamily. In humans, it is encoded by the SERPINA3 gene. Alpha 1-antichymotrypsin inhibits the activity of certain enzymes called proteases, such as cathepsin G that is found in neutrophils, and chymases found in mast cells, by cleaving them into a different shape or conformation. This activity protects some tissues, such as the lower respiratory tract, from damage caused by proteolytic enzymes.[2] This protein is produced in the liver, and is an acute phase protein that is induced during inflammation.