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特許 係属中 Periodontitis /ˌpɛrioʊdɒnˈtaɪtɪs/ or pyorrhea /ˌpaɪəˈriə/ is a set of inflammatory diseases affecting the periodontium, i.e., the tissues that surround and support the teeth. Periodontitis involves progressive loss of the alveolar bone around the teeth, and if left untreated, can lead to the loosening and subsequent loss of teeth. Periodontitis is caused by microorganisms that adhere to and grow on the tooth's surfaces, along with an over-aggressive immune response against these microorganisms.