Cyclopropanation

特許 係属中 Cyclopropanation refers to any chemical process which generates cyclopropane rings. It is an important process in modern chemistry as many useful compounds bare this motif; for example pyrethroids and a number of quinolone based antibiotics (Ciprofloxacin, Sparfloxacin, etc.). However the high ring strain present in cyclopropanes makes them challenging to produce and generally requires the use of highly reactive species, such as carbenes, ylids and carbanions.