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特許 権利維持 Biofilm formation occurs when free floating microorganisms attach themselves to a surface. They secrete extracellular polymers that provide a structural matrix and facilitate adhesion. Because biofilms protect the bacteria, they are often more resistant to traditional antimicrobial treatments, making them a serious health risk.[1] For example, there are more than one million cases of catheter-associated urinary tract infections (CAUTI) reported each year, many of which can be attributed to biofilm-associated bacteria.