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特許 係属中 Signal transducer and activator of transcription 3, also known as STAT3, is a transcription factor which in humans is encoded by the STAT3 gene. The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by receptor-associated kinases and then form homo- or heterodimers that translocate to the cell nucleus, where they act as transcription activators.
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