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特許 係属中 Leptin (from Greek λεπτός leptos, "thin"), the "satiety hormone", is a hormone made by fat cells, which regulates the amount of fat stored in the body. It does this by adjusting both the sensation of hunger, and adjusting energy expenditures. Hunger is inhibited (satiety) when the amount of fat stored reaches a certain level. Leptin is then secreted and circulates through the body, eventually activating leptin receptors in the arcuate nucleus of the hypothalamus.