Indentification of biopolymer passing through nanopore

特許 係属中 Nanopore sequencing is a method under development since 1995 [1][2] for determining the order in which nucleotides occur on a strand of DNA. A nanopore is simply a small hole, of the order of 1 nanometer in internal diameter. Certain porous transmembrane cellular proteins act as nanopores, and nanopores have also been made by etching a somewhat larger hole (several tens of nanometers) in a piece of silicon, and then gradually filling it in using ion-beam sculpting methods which results in a much smaller diameter hole: the nanopore.