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特許 係属中 Melanocortin receptors are members of the rhodopsin family of 7-transmembrane G protein-coupled receptors. These receptors are inhibited by endogenous inverse agonists agouti signalling peptide and agouti-related peptide,[6] and activated by synthetic (i.e. afamelanotide) and endogenous agonist melanocyte-stimulating hormones.