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特許 係属中 Ubiquitin is a small (8.5 kDa) regulatory protein that has been found in almost all tissues (ubiquitously) of eukaryotic organisms. It was discovered in 1975[1] by Goldstein and further characterized throughout the 1970s and 1980s.[2] There are four genes in the human genome that produce ubiquitin; UBB, UBC, UBA52 and RPS27A.