Myeloid derived suppressor cell

特許 係属中 MDSC (myeloid-derived suppressor cells) are a heterogenous population of immune cells from the myeloid lineage (a cluster of different cell types that originate from bone marrow stem cells), to which dendritic cells, macrophages and neutrophils also belong. However, MDSCs possess strong immunosuppressive activities rather than immunostimulatory properties. The word "myeloid" was originated from Greek language ("Myelos" +"eidos"), meaning "bone marrow" or "spinal cord". Myeloid cells interact with T cells (the effector immune cells that kill pathogens, infected and cancer cells) to regulate their functions, some of which are still under heated debate and close examination by the scientific community.