p97 protein

特許 権利維持 Transitional endoplasmic reticulum ATPase (TER ATPase) also known as valosin-containing protein (VCP) is an enzyme that in humans is encoded by the VCP gene. Valosin-containing protein (VCP) is a type II member of AAA+-ATPase family. It functions as a ubiquitin segregase that remodels multimeric protein complexes by extracting polyubiquitinated proteins for recycling or degradation by the proteasome. VCP subserves a broad array of cellular functions including mitochondrial quality control, autophagy, vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes.