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特許 係属中 The presence of endotoxins in the blood is called endotoxemia. It can lead to septic shock, if the immune response is severely pronounced.[30] Moreover, endotoxemia of intestinal origin, especially, at the host-pathogen interface, is considered to be an important factor in the development of alcoholic hepatitis,[31] which is likely to develop on the basis of the small bowel bacterial overgrowth syndrome and an increased intestinal permeability.