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特許 係属中 Transferrins are iron-binding blood plasma glycoproteins that control the level of free iron in biological fluids.[1] Human transferrin is encoded by the TF gene.[2] Transferrin glycoproteins bind iron very tightly, but reversibly. Although iron bound to transferrin is less than 0.1% (4 mg) of the total body iron, it is the most important iron pool, with the highest rate of turnover (25 mg/24 h). Transferrin has a molecular weight of around 80 KDa and contains two specific high-affinity Fe(III) binding sites.