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特許 係属中 Mutations in this gene have been associated with Parkinson's disease type 8.[13] The Gly2019Ser mutation in LRRK2 is a relatively common cause of familial Parkinson's Disease in Caucasians.[14] It may also cause sporadic Parkinson's Disease. The mutated Gly amino acid is conserved in all kinase domains of all species.
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