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特許 係属中 APP is an integral membrane protein whose proteolysis generates beta amyloid ranging from 39- to 42- amino acid peptide. Although biological function of APP are not known, it is predicted that APP may play a role during neuroregeneration, and regulation of neural activity, connectivity, plasticity, and memory. Recent researches have shown that large soluble APP (sAPP)[8] that are present in CSF may serve as a novel potential biomarkers of Alzheimer's disease.
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