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特許 係属中 Cotransformation is the simultaneous transformation of two or more genes. Only genes in the same chromosomal vicinity can be transformed; the closer together the genes lie, the more frequently they will be cotransformed. By contrast, genes sufficiently far apart that they cannot appear together on a fragment of donor[disambiguation needed] DNA will almost never be cotransformed, because transformation is so inefficient that recipient cells usually take up only a single DNA.