Cyclosporine A

特許 係属中 xCiclosporin (INN/BAN) (pronounced /ˌsaɪkləˈspɔrɪn/);[1] cyclosporine (USAN); cyclosporin (former BAN); or ciclosporin A,[2] cyclosporine A, or cyclosporin A (often shortened to CsA) is an immunosuppressant drug widely used in organ transplantation to prevent rejection. It reduces the activity of the immune system by interfering with the activity and growth of T cells.[3][4] It was initially isolated from the fungus Tolypocladium inflatum (Beauveria nivea), found in a soil sample obtained in 1969 from Hardangervidda, Norway, by Hans Peter Frey, a Sandoz biologist.