CFTR protein

特許 係属中 Cystic fibrosis transmembrane conductance regulator (CFTR) is a membrane protein[1] in vertebrates that is encoded by the CFTR gene.[2] CFTR is an ABC transporter-class ion channel that codes for a protein that conducts chloride[3] and thiocyanate[4] ions across epithelial cell membranes. Mutations of the CFTR gene affecting chloride ion channel function lead to dysregulation of epithelial fluid transport in the lung, pancreas and other organs, resulting in cystic fibrosis.