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特許 権利維持 Premature rupture of membranes (PROM), or pre-labor rupture of membranes, is a condition that occurs in pregnancy. It is defined as rupture, or breakage, of the amniotic sac more than one hour before the onset of labor.[1] The sac, or "membranes" contain amniotic fluid which surrounds and protects the fetus in the womb. After rupture, the amniotic fluid leaks out of the uterus through the vagina. This is informally known as one's "water breaking".