Toll-like receptor 11

特許 係属中 Toll-like receptor 11 (TLR11) is a protein that in humans is encoded by the gene TLR11. TLR11 belongs to the toll-like receptor (TLR) family and the interleukin-1 receptor/toll-like receptor superfamily. By recognizing flagellin and/or profilin present on certain microbes, it helps propagate a host immune response. TLR11 plays a fundamental role in both the innate and adaptive immune responses, through the activation of Tumor necrosis factor-alpha,[1] the Interleukin 12 (IL-12) response,[2] and Interferon-gamma (IFN-gamma) secretion.