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特許 権利維持 In an analogous way to FET devices in which the modulation of conductance (flow of electrons/holes) in the semiconductor, between the input (source) and the output (drain) terminals, is controlled by electrostatic potential variation (gate-electrode) of the charge carriers in the device conduction channel, the methodology of a Bio/Chem-FET is based on the detection of the local change in charge density, or so-called “field effect”, that characterizes the recognition event between a target molecule and the surface receptor.