Pseudotyping is the process of producing viruses or viral vectors in combination with foreign viral envelope proteins. The result is a pseudotyped virus particle.[1] With this method, the foreign v...
Ankle prosthesis
Syntaxins are a family of membrane integrated Q-SNARE proteins participating in exocytosis.
Interferon alfa (INN) or HuIFN-alpha-Le, trade name Multiferon, is a pharmaceutical drug composed of natural interferon alpha (IFN-α) obtained from the leukocyte fraction of human blood following i...
Immune stimulatory oligonucleotides
Tat contains a protein transduction domain, and is therefore known as a cell-penetrating peptide.[14] Originally[15] characterised by Frankel and Pabo (1988)[16] and Green and Loewenstein (1988),[1...
Bardet-Biedl syndrome 4 is a protein that in humans is encoded by the BBS4 gene.[1][2][3] This gene encodes a protein which contains tetratricopeptide repeats (TPR), similar to O-linked N-acetyl...
Biofilms have been found to be involved in a wide variety of microbial infections in the body, by one estimate 80% of all infections.[35] Infectious processes in which biofilms have been implicated...
Juvenile polyposis syndrome is a syndrome characterized by the appearance of multiple juvenile polyps in the gastrointestinal tract. Polyps are abnormal growths arising from a mucous membrane. Thes...
Adenoviruses (members of the family Adenoviridae) are medium-sized (90–100 nm), nonenveloped (without an outer lipid bilayer) viruses with an icosahedral nucleocapsid containing a double stranded D...
Hybridoma technology is a technology of forming hybrid cell lines (called hybridomas) by fusing an antibody-producing B cell with a myeloma (B cell cancer) cell that is selected for its ability to ...
Beta defensins are a family of mammalian defensins. The beta defensins are antimicrobial peptides implicated in the resistance of epithelial surfaces to microbial colonization. Defensins are 2-6...
Candidiasis is a fungal infection due to any type of Candida (a type of yeast).[1] When it affects the mouth, it is commonly called thrush.[1] Signs and symptoms include white patches on the tongue...
Immunostimulating nucleic acids
β-Hydroxy β-methylbutyric acid (HMB), or β-hydroxy β-methylbutyrate, is a metabolite of the essential amino acid leucine and is synthesized in the human body. Its part in protein synthesis was disc...
Glaucoma is a term describing a group of ocular (eye) disorders that result in optic nerve damage, often associated with increased fluid pressure in the eye (intraocular pressure) (IOP).[1] The dis...
Calpastatin is a protein that in humans is encoded by the CAST gene.[1][2][3][4] The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It con...
The soybean (US) or soya bean (UK, AU) (Glycine max)[2] is a species of legume native to East Asia, widely grown for its edible bean which has numerous uses. The plant is classed as an oilseed rath...
Porcine circovirus (PCV) is a single-stranded DNA virus (class II), that is nonenveloped with an unsegmented circular genome.[1] The viral capsid is icosahedral and approximately 17 nm in diameter....
The process of finding a new drug against a chosen target for a particular disease usually involves high-throughput screening (HTS), wherein large libraries of chemicals are tested for their abilit...
