Transient receptor potential cation channel, subfamily M, member 2, also known as TRPM2, is a protein that in humans is encoded by the TRPM2 gene. The TRPM2 gene is highly expressed in the brain a...
Neuroregeneration refers to the regrowth or repair of nervous tissues, cells or cell products. Such mechanisms may include generation of new neurons, glia, axons, myelin, or synapses. Neuroregenera...
Cationic peg-lipids
Microglia are a type of glial cell that are the resident macrophages of the brain and spinal cord, and thus act as the first and main form of active immune defense in the central nervous system (CNS).
Transferrins are iron-binding blood plasma glycoproteins that control the level of free iron in biological fluids.[1] Human transferrin is encoded by the TF gene.
Antimicrobial peptides (also called host defense peptides) are part of the innate immune response and are found among all classes of life. Fundamental differences exist between prokaryotic and euka...
CNS Malignancies
The alpha helix (α-helix) is a common secondary structure of proteins and is a righthand-coiled or spiral conformation (helix) in which every backbone N-H group donates a hydrogen bond to the backb...
Quadrupole fields
Drugs that block the CXCR4 receptor appear to be capable of "mobilizing" hematopoietic stem cells into the bloodstream as peripheral blood stem cells. Peripheral blood stem cell mobilization is ver...
Measuring tissue mechanical properties
Cancer Listeni/ˈkænsər/, also known as a malignant tumor or malignant neoplasm, is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the bo...
Treating diseases of body passageways
A stent graft or covered stent is type of vascular stent with a fabric coating that creates a contained tube but is expandable like a bare metal stent. Covered stents are used in endovascular surgi...
Photodynamic therapy (PDT), sometimes called photochemotherapy, is a form of phototherapy using nontoxic light-sensitive compounds that are exposed selectively to light, whereupon they become toxic...
An Endoglycosidase is an enzyme that releases oligosaccharides from glycoproteins or glycolipids. It may also cleave polysaccharide chains between residues that are not the terminal residue, althou...
Hyaluronan /haɪˈæljʊrənən/ (also called hyaluronic acid /ˌhaɪəl.jʊˈrɒnɨk/, hyaluronate /ˌhaɪəlˈjʊərəneɪt/ or /ˌhaɪəˈlʊərəneɪt/, or HA) is an anionic, nonsulfated glycosaminoglycan distributed widel...
Control of protein levels
The innate immune system, also known as the nonspecific immune system and the first line of defense,[1] is an important subsystem of the overall immune system that comprises the cells and mechanism...
